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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4L
All Species:
27.27
Human Site:
S41
Identified Species:
50
UniProt:
Q96PU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PU5
NP_001138436.1
975
111932
S41
K
K
D
I
F
G
A
S
D
P
Y
V
K
L
S
Chimpanzee
Pan troglodytes
XP_001140254
911
104904
S41
K
K
D
I
F
G
A
S
D
P
Y
V
K
L
S
Rhesus Macaque
Macaca mulatta
XP_001088661
1010
115306
S72
K
K
D
I
F
G
A
S
D
P
Y
V
K
L
S
Dog
Lupus familis
XP_533393
1027
117927
S93
K
Y
E
I
F
S
Y
S
D
P
Y
V
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFI0
1004
115400
S69
K
K
D
I
F
G
A
S
D
P
Y
V
K
L
S
Rat
Rattus norvegicus
Q62940
887
102376
G44
D
T
C
E
P
P
C
G
C
W
E
L
N
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
S115
A
G
E
E
A
S
F
S
G
V
I
E
E
A
N
Chicken
Gallus gallus
XP_424462
1045
119140
S111
K
K
D
I
F
G
A
S
D
P
Y
V
K
L
S
Frog
Xenopus laevis
Q2TAS2
751
86306
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
S91
K
K
D
I
F
G
A
S
D
P
Y
V
R
I
D
Honey Bee
Apis mellifera
XP_395191
782
90150
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.4
90.8
N.A.
94.3
48
N.A.
43.9
85.6
34.1
34.3
N.A.
47.2
49.4
N.A.
N.A.
Protein Similarity:
100
93.4
93.7
92.2
N.A.
95.6
60
N.A.
54
88.4
49
49.5
N.A.
61.8
61.1
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
100
6.6
N.A.
6.6
100
0
0
N.A.
80
0
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
13.3
N.A.
26.6
100
0
0
N.A.
93.3
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
47
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
47
0
0
0
0
0
54
0
0
0
0
0
8
% D
% Glu:
0
0
16
16
0
0
0
0
0
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
54
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
47
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
54
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
54
47
0
0
0
0
0
0
0
0
0
0
47
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
47
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
8
0
0
0
54
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
16
0
62
0
0
0
0
0
0
54
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
54
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _